First 2.5 Weeks of April

• Tues 4/3:  Check off Enzyme Worksheet and go over.  Finish enzyme notes.  Introduce Enzyme Lab and try first protocol.  Read 2.5 and 8.1 if not already.
• Thurs 4/5:  Do last 2 protocols for Enzyme Lab and decide what protocol and which independent variable (pH, temperature, or substrate concentration) your group wants to manipulate.  Start working on pre-write (each individual!).  Blind taste test of regular and lactose-free milk.  Complete focused question, background, variables, procedure and data table before you take come in to take data next Monday!  See lab guidelines document to help.
• Mon 4/9:  Get pre-write for Enzyme Lab checked off.  Carefully and efficiently take data.  Everyone should record data and observations.  When finished, clean up and start processing your data.  
• Wed 4/11:  Discuss lab write-up and take some time to work on data-processing and/or conclusion/evaluation.  Introduce Biotech topics and take some notes on stem cells.  Boston Children's Hospital Stem Cell Activity.   Read 3.5.
• Fri 4/13:  No School.  Teacher work day for the end of 3rd Quarter.
• Mon 4/16: Go over Evaluation for Enzyme Lab.  Finish Stem Cell Simulation and more work on Enzyme Lab.   PCR and introduce gel electrophoresis technique.   First draft of Enzyme Lab due Wed for peer review.
• Wed 4/18:  Peer review of Enzyme Lab.  Final draft due Thurs 4/26 through turnitin.com.  Micropipetting practice.

About the test on Wednesday March 21

The Replication, Transcription, Translation Test on Wed, March 21 will have the following:
1)  12-16 Multiple Choice Questions
2)  Some questions using the genetic code:  writing code, translating code, and the consequences of a change (mutation) to the sequence
3)  Describe the process of replication using important vocabulary (leading strand, lagging strand, the 5 enzymes, Okazaki fragments, etc.
4)  Describe the process of translation using important vocabulary and including the 3 main steps.
5)  Describe the structure of nucleosomes and their role in control of gene expression.  Include the difference between methylation and acetylation and also include the implications of epigenetics.

March 2018

• Mon 3/5:  Take Genetics Test.  Pick up Replication Worksheet and start working on it.  To be done by Fri 3/9.  Read 2.7
• Wed 3/7:  Process of Replication and some scientific history.  Replication Simulation done in table groups.  Work on Replication worksheet.  Read 2.7 and 7.1.
• Fri 3/9:  Replication Worksheet check off and go over.  Process of transcription and control of gene expression.  Short video on Epigenetics.  Read 7.2.
• Tues 3/13:  Review Transcription and Go over the Process of Translation.  Read 7.3.
• Thurs 3/15:  Genetic code and protein structure.  Review the whole process of translation.
• Mon 3/19:  Review for Replication, Transcription, and Translation test to be taken on Wednesday 3/21.
• Wed 3/21:  Replication, Transcription, and Translation Test.  Start Enzymes.
• Fri 3/23:  Enzyme structure and function.   Read 8.1.

Genetics Test on Monday, March 5th!

This is what will be on the Genetics Test.  Make sure that you study these concepts and come in for help during FLEX this week if you need it.

• Part I:  20 or so multiple choice questions on all kinds of topics.  We will play some Kahoot to help identify the types of questions
• Part II:  a) Chi-Squared Problem.  You will be given the equation and critical value chart, but you will need to know how to calculate expected values, do the math for the equation, and interpret the results.  
• b)  Dihybrid cross that will involve identifying the gametes, filling in the Punnett Grid, and listing the ratios of the results 
•  c)  Describe the genetic cause, symptoms, treatment, and interesting facts for a genetic disorder.  Out of hemophilia, sickle cell anemia, Down Syndrome, Turner Syndrome, cystic fibrosis, and Huntington's.  We will draw 3 of these from a "hat" and you will write about one.  The University of Utah site (Learn Genetics) linked on my website has good info on all of them except hemophilia, and hemophilia is written up in the book (pp 180-181). 
• d)  A short question on a pedigree problem 

Genetic Disorder Poster Project (due Wed, 2/21)

For your genetic disease, find and present the following information on a poster!!

1. I recommend using Learn Genetics Website (except for Hemophilia and Duchenne’s Muscular Dystrophy)
2. Type of inheritance (chromosomal, single gene, dominant, recessive, sex-linked, etc).  Include all that apply.
3. Describe what it does to the body in terms of biochemistry
4. List symptoms, treatments, patient prognosis
5. Interesting Facts
6. Other?

2nd Half of February

• Monday 2/12:  Science OAKS test for Juniors, followed by return to classroom to work on genetics problems and pedigree problems.  Read 10.2.
• Wed 2/14:   Hand in Genetics Problems.  Genetic testing and genetic disorders. Causes of mutations.   In groups, research a genetic disorder and make an informational poster about it.  Hand out Pedigree Worksheet.
• Fri 2/16:  Check off Pedigree Worksheet.  Finish posters and display them.   Exceptions to Mendel's rules.  Polygenic inheritance.  Linked genes.  DBQ on pp. 452-453.
• Wed 2/21:  Snow Day
• Frid 2/23:  Finish linked genes and gene mapping.  Chi-squared test and flower cross.  DBQ on p. 454.
• Tues 2/27:  After ACT Testing.  Check off DBQ's.  Finish chi-squared activity.  Present Genetic Disease posters.
• Thurs 3/1:  Finish going over Genetic Diseases and DBQ's.  Play Kahoot to review for Genetics Test now on Monday 3/5.

First 2 Weeks of the New Semester

• Wed 1/31:  Final Exams, look at them, and then recollect.  Go over what we will cover 2nd semester.  Start 3.1 and 3.2 book work.  Please finish through the 3.1 questions on your own time if you are not there yet.
• Fri 2/2:  Review 3.1 concepts and questions.  Any questions on 3.2 so far?  Video on Mendel.  Work on 3.2 questions, answering them in your notebook.  Get them checked off if you complete them today.  Otherwise get them checked off on Tuesday.  Read 3.4.
• Tues 2/6:  Check off 3.1 and 3.2 questions and go over.  Types of genetic problems:  Punnett grids, problems with codominance, X-linked problems.  Start genetic problems from the old text book.  
• Thurs 2/8:  More on genetics problems.  Dihybrid crosses.  Work on genetic problems.  Due next Wed 2/14.