Update of What We Have Covered and Will Cover

• Tues 3/10:  Science State Testing.  Thank you all for being so cooperative with this!  I'm not sure how this will get finished in light of corona virus, but I'm assuming that extensions will be made and you will be pulled out to finish it later when we get back to school.
• Thurs 3/12:  Go over the Hershey-Chase experiment and notes on DNA Replication.  Work on the 7.1 questions that I put on the website.  Get checked off when you finish.
• Mon 3/16:  Review DNA replication.  I have put several videos on this website to help you go over the process.  Finish doing the 2.7 and 7.1 questions in your notes.  You can email me a photo of this work and I will check it off.  Read 7.2 and go over the Transcription Notes.  
• Wed 3/18:  Watch the Video "Epigenetics: The Hidden Life of our Genes".  It is 53 minutes.  We used to show "Ghost in Your Genes" as the primary video on epigenetics and I have also included an 8 minute clip of that.  Please watch these and write 2-3 paragraphs about how epigenetics works and how it relates to the topic of transcription.  I would also like you to include answers to the 2 DBQs in 7.2 on twin studies.  Please submit these to turnitin.com by Friday 3/20!
• Fri 3/20:  Read the transcription and translation sections of 2.7 (pp 116-122) and do the Genetic Code worksheet on my website.   I will post a video to help you get started on this.  
• Moving forward:  Read 7.3 and go through the Translation Notes.  I will post videos to help with this material.

2.7 and 7.1 Work to be Done after the Genetics Test on Friday 3/6

1. (Starting in 2.7) What does it mean to say the DNA replication is semi-conservative?
2. Read the section on the Meselson-Stahl experiment, describe the evidence, and explain what it means.
3. Do the DBQ on pp 113-114
4. What does helicase do?
5. What does DNA polymerase do?
6. (Moving to 7.1)  What were Hershey and Chase trying to determine in their experiment?
7. Outline the Hershey-Chase experiment, including the results.
8. What is a nucleosome and what is its role in DNA packing?
9. Do the DBQ on p. 349 (this one is tricky, but I will give some background on it in class)
10. Outline the process of DNA replication.  You may draw a diagram.  (We will go over this in class).
11. What direction does DNA replication go and why is it limited in this way?
12. What are some of the functions of non-coding DNA?

Genetics Unit

• Tues 2/18:  Notes on basic genetics, how to do a monohybrid cross with simple dominance and co-dominance.  ABO blood group crosses.  Dihybrid crosses and the multiplication rule.  Work on the Old Book Genetics Problems (you can skip #6 for now).  Do problems on separate paper that you can turn in.  Show work and/or explain reasoning.  Work can include Punnett grids, diagrams, and showing mathematical work.  Read 3.4 if not already.
• Thurs 2/20:  Go over some of the genetics problems and introduce pedigrees.  Sex-linked genes.   More work time on genetics problems, to be turned in on Monday 2/24.  Hand out pedigree worksheet.  Start reading 10.2.
• Mon 2/24:  Turn in genetics problems.  Check off pedigree worksheet.  Notes on causes of genetic diseases and some common single gene disorders.  Polygenic inheritance.  Genetics of Race Video.  Research a single-gene disorder, including where on the chromosomes it occurs, what it does to impact the body, symptoms, treatments, outcomes, interesting facts, etc.  
• Wed 2/26:  Notes on linked genes, recombinants, calculating frequencies of recombination, and a little bit on gene mapping.  Introduce chi-squared.  Some DBQs to be done in your notebook:  pp. 452-453 and p. 454 (chi-squared).
• Fri 2/28:  Chi-squared and flower activity.  Answer questions in pairs and get checked off..  Read 10.2 if not already.  Review for Genetics Test to be taken next Friday 3/6.
• Tues 3/3:  Counselors will be here to do a 30 minute presentation.  Play Kahoot Review for Genetics Test.
• Wed 3/4:  SAT Testing Day.  There will be a Full 8 schedule for those not taking the test.
• Friday 3/6:  Genetics Test.  Start replication.  Read the first part of 2.7 and 7.1.

What's On the Meiosis and Genes Short Test on Thursday, February 13?

• Be able to describe all the phases of meiosis, in particular, make sure you understand the difference between Meiosis I and Meiosis II
• Be able to identify phases of meiosis in simple diagrams or pictures
• Be able to draw and label the stages of crossing over making clear the before, during, and after.  I recommend 4 stages as they showed in the book in 10.1.  Be able to distinguish between homologous chromosomes, sister chromatids, and nonsister chromatids.
• Be able to describe the significance of independent assortment and how it adds to the variety of gametes.
• Basic vocabulary involving genes and chromosomes.  In addition you should be able to distinguish between genes, chromosomes, and genomes
• Be able to describe how nondisjunction occurs and be able to describe two disorders caused by nondisjunction
• Be able to discuss the 2 methods of obtaining fetal cells for karyograms, including how they are done, benefits, and risks.

The First Few Weeks of the 2nd Semester!

• Tues 1/28:  Hand back Semester Final Exams, check them over, and recollect.  Introduction to what we will cover this semester.  Notes on meiosis, how it is different from mitosis, and the 8 phases.  Do first side of meiosis worksheet, identifying the phases.  Read 3.3.
• Thurs 1/30:  Notes on the Higher Level meiosis.  Synapsis and crossing over.  Do the "creature" activity on the back side of the meiosis worksheet.  Using 2 cards, determine the genotypes and phenotypes of your creature family and then draw a family portrait with your table group.  Read 10.1 (higher level meiosis).
• Mon 2/3:  Notes on genes, mutations, gene mapping, the Human Genome Project, etc.  Finish the Family Portrait if necessary.  Read 3.1.
• Wed 2/5:  Notes on chromosomes, plasmids, genome sizes, and chromosome numbers.  Do DBQ's on pp. 153, 156, and 159 in your notebook.  Read 3.2.
• Fri 2/7:  Karyograms and nondisjunction.  Check off DBQ's and go over them.  Wrap up the unit.
• Tues 2/11:  Review Meiosis and Genes and play Kahoot for Short Test to be taken on Thursday.  If time, start Genetics.
• Thurs 2/13:  Short Meiosis and Genes Test.  Introduce Mendel and the principles of inheritance.  Start reading 3.4.

What Are We Doing Second Semester??

Here are the topics and syllabus sections for 2nd semester:

1. Meiosis and Genetics:  3.3, 10.1, 3.1, 3.2
2. Genetics:  3.4, 10.2
3. Replication, Transcription, and Translation:  2.7, 7.1, 7.2, 7.3
4. Enzymes:  2.5, 8.1
5. Biotechnology:  3.5 and a few other sections
6. Plants:  9.1, 9.2, 9.3, 9.4

What's On That Cell Cycle Quiz on Tuesday 1/14?

• Be able to outline the events of the cell cycle, starting with interphase (include all 3 parts of interphase) and ending with cytokinesis.  Be thorough!
• Be able to distinguish between cell division in prokaryotes and eukaryotes, including why these differences are necessary
• Be able to distinguish between cell division in plant cells and animal cells, including why these differences are necessary
• Be able to describe several things that you see in an indicated cell in an onion root tip slide and determine which phase of mitosis it is (we are including interphase, even though it officially isn't a phase of mitosis).